USCIS Application Support Center — Greer, SC
The Application Support Center - Greer, SC is a USCIS Application Support Center (ASC) at USCIS Application Support Center, 501 Pennsylvania Avenue, Greer, SC 29652. ASCs are the offices where USCIS takes biometrics (fingerprints, photographs and signatures) for applications that require them. In USCIS’s field-office-by-ZIP file dated August 28, 2026, 217 ZIP codes in 35 counties (NC, SC, TN, VA) are assigned to this ASC.
General information, not legal advice. For your specific case, talk to an immigration attorney or an accredited representative.
Quick reference
| As listed on the USCIS office page (checked October 17, 2026) | |
|---|---|
| Address | USCIS Application Support Center, 501 Pennsylvania Avenue, Greer, SC 29652 |
| Hours | Monday to Friday, 8:00 a.m. - 4:00 p.m.; closed Saturday and Sunday |
| Military personnel | This office provides services to military personnel from 9:00AM to 3:00PM, Monday through Friday. |
| Parking and accessibility | There is parking available. ACCESSIBILITY: This office is accessible to people with disabilities. |
| Public transportation | There is no public transportation available. |
| USCIS page | Application Support Center - Greer, SC |
Getting there: USCIS driving directions
The ASC’s USCIS page gives these driving directions (quoted as published):
From Interstate 85: Get off on Exit 56 for Highway 14. Head North on Highway 14. Drive approximately 6 miles. Turn left onto Pennsylvania Avenue just as you cross the bridge entering the city of Greer. Drive approximately 1 mile. The ASC is located on the left across the street from the Greer US Post Office. Traveling North: Take Interstate 395 North toward Greenville. Take Exit 40A and merge onto South Caroline 291 North/North Pleasantburg Drive. Continue to follow North Pleasantburg Drive. Make a slight right onto Wade Hampton Boulevard. Turn right onto Lloyd Street. Make a slight left onto West Poinsett Street. Turn right at the first cross street onto Pennsylvania Avenue. The ASC will be on the right. Traveling South: Head east on South Carolina 101 South/South Carolina 414 East toward County Road 44/Glassy Road. Take the first right onto South Carolina 101 South. Turn left onto South Carolina 101 South/South Carolina 290/County Road 415/Locust Hill Road. Continue to follow South Carolina 101 South/South Carolina 290. Turn left onto West Wade Hampton Boulevard. Turn right onto Lloyd Street. Make a slight left onto West Poinsett Street. Turn right at the first cross street onto Pennsylvania Avenue. The ASC will be on the right. Traveling East: Take the South Carolina 8 East/Hampton Avenue. Continue to follow South Carolina 8 East. Continue onto West Main Street. Turn right onto South Pendleton Street. Turn left to merge onto US-123 North. Turn left onto North Church Street. Turn right onto Wade Hampton Boulevard. Turn right onto Lloyd Street. Make a slight left onto West Poinsett Street. Turn right at the first cross street onto Pennsylvania Avenue. The ASC will be on the right. Traveling Southwest: Take Interstate 85 South. Take Exit 66 for US-29 toward Wellford/Lyman. Turn right onto US-29 South/East Greenville Highway/Spartanburg Highway. Continue to follow US-29 South. Turn left onto Lloyd Street. Make a slight left onto West Poinsett Street. Turn right at the first cross street onto Pennsylvania Avenue. The ASC will be on the right.
ZIP codes and counties USCIS assigns to this ASC
USCIS’s field-office-by-ZIP file (dated August 28, 2026) names an ASC for every ZIP code. These are the counties with ZIP codes assigned to the Greer ASC, with up to four of their cities (most ZIP codes first, then alphabetical). USCIS assigns ZIP codes, not whole counties, so a county can be split between ASCs.
| County | State | ZIP codes | Cities |
|---|---|---|---|
| Greenville | SC | 20 | Greenville, Greer, Simpsonville, Cleveland, … |
| Spartanburg | SC | 20 | Spartanburg, Boiling Springs, Campobello, Chesnee, … |
| Buncombe | NC | 14 | Asheville, Alexander, Arden, Barnardsville, … |
| Henderson | NC | 10 | Hendersonville, East Flat Rock, Etowah, Flat Rock, … |
| Pickens | SC | 10 | Clemson, Easley, Central, Liberty, … |
| Newberry | SC | 8 | Chappells, Kinards, Little Mountain, Newberry, … |
| Sullivan | TN | 8 | Kingsport, Blountville, Bluff City, Bristol, … |
| Transylvania | NC | 8 | Balsam Grove, Brevard, Cedar Mountain, Lake Toxaway, … |
| Washington | TN | 8 | Johnson City, Fall Branch, Jonesborough, Limestone, … |
| Greene | TN | 7 | Greeneville, Afton, Chuckey, Midway, … |
| Greenwood | SC | 7 | Greenwood, Bradley, Hodges, Ninety Six, … |
| Hawkins | TN | 7 | Bulls Gap, Church Hill, Eidson, Mooresburg, … |
| Laurens | SC | 7 | Clinton, Cross Hill, Gray Court, Joanna, … |
| Rutherford | NC | 7 | Bostic, Ellenboro, Forest City, Lake Lure, … |
| Washington | VA | 7 | Abingdon, Bristol, Damascus, Glade Spring, … |
| Cocke | TN | 6 | Bybee, Cosby, Del Rio, Hartford, … |
| Hamblen | TN | 6 | Morristown, Lowland, Russellville, Talbott, … |
| Haywood | NC | 6 | Waynesville, Canton, Clyde, Lake Junaluska, … |
| Sevier | TN | 6 | Sevierville, Gatlinburg, Kodak, Pigeon Forge, … |
| Jefferson | TN | 5 | Dandridge, Jefferson City, New Market, Strawberry Plains, … |
| McCormick | SC | 5 | Clarks Hill, Mc Cormick, Modoc, Mount Carmel, … |
| Carter | TN | 4 | Elizabethton, Hampton, Roan Mountain, Watauga |
| Polk | NC | 4 | Columbus, Mill Spring, Saluda, Tryon |
| Union | SC | 4 | Buffalo, Carlisle, Jonesville, Union |
| Madison | NC | 3 | Hot Springs, Mars Hill, Marshall |
| McDowell | NC | 3 | Marion, Nebo, Old Fort |
| Unicoi | TN | 3 | Erwin, Flag Pond, Unicoi |
| Cherokee | SC | 2 | Gaffney |
| Fairfield | SC | 2 | Blair, Jenkinsville |
| Hancock | TN | 2 | Kyles Ford, Sneedville |
| Johnson | TN | 2 | Butler, Shady Valley |
| Mitchell | NC | 2 | Bakersville, Spruce Pine |
| Yancey | NC | 2 | Burnsville, Green Mountain |
| Bristol City | VA | 1 | Bristol |
| Cleveland | NC | 1 | Mooresboro |
Every ZIP code assigned to the Greer ASC, by city
From the same USCIS file (Aug 28, 2026), retired ZIP codes excluded:
- Abingdon, VA: 24210, 24211
- Afton, TN: 37616
- Alexander, NC: 28701
- Arden, NC: 28704
- Asheville, NC: 28801, 28803, 28804, 28805, 28806
- Bakersville, NC: 28705
- Balsam Grove, NC: 28708
- Barnardsville, NC: 28709
- Black Mountain, NC: 28711
- Blair, SC: 29015
- Blountville, TN: 37617
- Bluff City, TN: 37618
- Boiling Springs, SC: 29316
- Bostic, NC: 28018
- Bradley, SC: 29819
- Brevard, NC: 28712
- Bristol, TN: 37620
- Bristol, VA: 24201, 24202
- Buffalo, SC: 29321
- Bulls Gap, TN: 37711
- Burnsville, NC: 28714
- Butler, TN: 37640
- Bybee, TN: 37713
- Campobello, SC: 29322
- Candler, NC: 28715
- Canton, NC: 28716
- Carlisle, SC: 29031
- Cedar Mountain, NC: 28718
- Central, SC: 29630
- Chappells, SC: 29037
- Chesnee, SC: 29323
- Chuckey, TN: 37641
- Church Hill, TN: 37642
- Clarks Hill, SC: 29821
- Clemson, SC: 29631, 29632
- Cleveland, SC: 29635
- Clinton, SC: 29325
- Clyde, NC: 28721
- Columbus, NC: 28722
- Cosby, TN: 37722
- Cowpens, SC: 29330
- Cross Hill, SC: 29332
- Damascus, VA: 24236
- Dandridge, TN: 37725
- Del Rio, TN: 37727
- Duncan, SC: 29334
- Easley, SC: 29640, 29642
- East Flat Rock, NC: 28726
- Eidson, TN: 37731
- Elizabethton, TN: 37643
- Ellenboro, NC: 28040
- Enoree, SC: 29335
- Erwin, TN: 37650
- Etowah, NC: 28729
- Fairview, NC: 28730
- Fall Branch, TN: 37656
- Flag Pond, TN: 37657
- Flat Rock, NC: 28731
- Fletcher, NC: 28732
- Forest City, NC: 28043
- Fountain Inn, SC: 29644
- Gaffney, SC: 29340, 29341
- Gatlinburg, TN: 37738
- Gerton, NC: 28735
- Glade Spring, VA: 24340
- Gray Court, SC: 29645
- Green Mountain, NC: 28740
- Greeneville, TN: 37743, 37745
- Greenville, SC: 29601, 29605, 29607, 29609, 29611, 29613, 29615, 29617
- Greenwood, SC: 29646, 29649
- Greer, SC: 29650, 29651
- Hampton, TN: 37658
- Hartford, TN: 37753
- Hendersonville, NC: 28739, 28791, 28792
- Hodges, SC: 29653
- Horse Shoe, NC: 28742
- Hot Springs, NC: 28743
- Inman, SC: 29349
- Jefferson City, TN: 37760
- Jenkinsville, SC: 29065
- Joanna, SC: 29351
- Johnson City, TN: 37601, 37604, 37614, 37615
- Jonesborough, TN: 37659
- Jonesville, SC: 29353
- Kinards, SC: 29355
- Kingsport, TN: 37660, 37663, 37664, 37665
- Kodak, TN: 37764
- Kyles Ford, TN: 37765
- Lake Junaluska, NC: 28745
- Lake Lure, NC: 28746
- Lake Toxaway, NC: 28747
- Landrum, SC: 29356
- Laurens, SC: 29360
- Leicester, NC: 28748
- Liberty, SC: 29657
- Limestone, TN: 37681
- Little Mountain, SC: 29075
- Lowland, TN: 37778
- Lyman, SC: 29365
- Maggie Valley, NC: 28751
- Marietta, SC: 29661
- Marion, NC: 28752
- Mars Hill, NC: 28754
- Marshall, NC: 28753
- Mauldin, SC: 29662
- Mc Cormick, SC: 29835
- Meadowview, VA: 24361
- Mendota, VA: 24270
- Midway, TN: 37809
- Mill Spring, NC: 28756
- Modoc, SC: 29838
- Mohawk, TN: 37810
- Moore, SC: 29369
- Mooresboro, NC: 28114
- Mooresburg, TN: 37811
- Morristown, TN: 37813, 37814
- Mosheim, TN: 37818
- Mount Carmel, SC: 29840
- Mount Carmel, TN: 37645
- Mountville, SC: 29370
- Nebo, NC: 28761
- New Market, TN: 37820
- Newberry, SC: 29108
- Newport, TN: 37821
- Ninety Six, SC: 29666
- Norris, SC: 29667
- Old Fort, NC: 28762
- Pacolet, SC: 29372
- Parrottsville, TN: 37843
- Pauline, SC: 29374
- Penrose, NC: 28766
- Pickens, SC: 29671
- Piedmont, SC: 29673
- Pigeon Forge, TN: 37863
- Piney Flats, TN: 37686
- Pisgah Forest, NC: 28768
- Plum Branch, SC: 29845
- Pomaria, SC: 29126
- Prosperity, SC: 29127
- Roan Mountain, TN: 37687
- Roebuck, SC: 29376
- Rogersville, TN: 37857
- Rosman, NC: 28772
- Russellville, TN: 37860
- Rutherfordton, NC: 28139
- Saluda, NC: 28773
- Sapphire, NC: 28774
- Sevierville, TN: 37862, 37876
- Seymour, TN: 37865
- Shady Valley, TN: 37688
- Silverstreet, SC: 29145
- Simpsonville, SC: 29680, 29681
- Six Mile, SC: 29682
- Sneedville, TN: 37869
- Spartanburg, SC: 29301, 29302, 29303, 29306, 29307
- Spindale, NC: 28160
- Spruce Pine, NC: 28777
- Strawberry Plains, TN: 37871
- Sunset, SC: 29685
- Surgoinsville, TN: 37873
- Swannanoa, NC: 28778
- Talbott, TN: 37877
- Taylors, SC: 29687
- Telford, TN: 37690
- Tigerville, SC: 29688
- Travelers Rest, SC: 29690
- Troy, SC: 29848
- Tryon, NC: 28782
- Unicoi, TN: 37692
- Union, SC: 29379
- Union Mills, NC: 28167
- Ware Shoals, SC: 29692
- Watauga, TN: 37694
- Waterloo, SC: 29384
- Waynesville, NC: 28785, 28786
- Weaverville, NC: 28787
- Wellford, SC: 29385
- White Pine, TN: 37890
- Whitesburg, TN: 37891
- Whitmire, SC: 29178
- Woodruff, SC: 29388
- Zirconia, NC: 28790
Field offices whose ZIP codes route here (from the same file):
- USCIS Greer Field Office: 85 ZIP codes
- USCIS Charlotte Field Office: 68 ZIP codes
- USCIS Nashville Field Office: 64 ZIP codes
Before your appointment: what USCIS says
- Go only with a notice. The ASC’s USCIS page says applicants need to appear at the assigned ASC on the appointment notice.
- What to bring. USCIS’s biometrics page lists your ASC appointment notice (Form I-797C), every notice if you received several, and valid photo identification (such as a Green Card, passport or driver’s license).
- Rescheduling. USCIS’s biometrics page says the request must be made through your USCIS online account (not by mail), before the original appointment, with good cause, and at least 12 hours before the appointment time; to use a different ASC you must reschedule in advance and select it. If the request is less than 12 hours from the appointment or you missed it, the page says to call the USCIS Contact Center at 800-375-5283 (TTY 800-767-1833).
- Closures. If the ASC closes for weather or a facility issue, USCIS says it reschedules the appointment automatically; it asks you to check its Office Closings page before traveling.
- No weapons. USCIS says federal law prohibits weapons such as firearms, knives, pepper spray and ammunition at any USCIS facility.
Related information
- USCIS Greer Field Office
- USCIS Charlotte Field Office
- USCIS Nashville Field Office
- All USCIS offices serving South Carolina
- Change of address with USCIS
Last verified: 2026-10-17. General procedural information for educational purposes, not legal advice; for your specific case, consult an immigration attorney or accredited representative. Office data comes from official USCIS pages and files and can change. Your appointment notice is what counts.